All research projects

The genetic basis of height extremes

Awarded $108,000 in funding
Over 3 years, starting in 2019

Collaborative research

Dr Louise Bicknell from the University of Otago is collaborating with paediatric endocrinologists and genetics researchers to identify potential causes of height extremes. Until recently, access to whole exome sequencing (the ability to read a person’s entire DNA make-up) has been limited, but greater access is now available.

Using genetics for a better understanding

Dr Bicknell and her team will assess the genes of children who are above or below three standard deviations from the mean on height (about 0.1% of the population). They hope to identify novel variants in already-known genes, as well as genes never before discovered.

Insights for families

It’s hoped these discoveries will enable appropriate genetic counselling for families. Additionally, families will no longer feel they have to look for answers, a process that involves a multitude of tests that cause stress and anxiety.

Cure Kids funding

Dr Bicknell is using a grant from Cure Kids to pay for exome sequencing and bioinformatic analysis to investigate the genetic alterations and learn more about the underlying causes of extreme stature in children.

Help fund our big research.

Every bit helps.