We are supporting with

Neurological and Neurodevelopmental Disorders

The brain is the most complicated organ

Neurological and neurodevelopmental disorders include a very broad range of conditions, different types of research, and many potential areas for discovery. For kids, these disorders typically occur when something is abnormal in their brain, nervous system or muscle cells.
1 Active project

Why is it a problem?

Why is it a problem?

What are they?

Neurological and neurodevelopmental disorders are dysfunctions in part of the brain or nervous system that result in physical or psychological symptoms that can affect a child’s behaviour, memory, or ability to learn. Common neurological and neurodevelopmental disorders are:

• ADHD (attention deficit hyperactivity disorder)

• Autism

• Brain Tumours

• Traumatic Brain Injury

• Cerebral Palsy

• Dyslexia

• Epilepsy

• Foetal Alcohol Syndrome

• Hydrocephalus

• Migraines

• Motor Neuron Disease

• Multiple Sclerosis (MS)

How do they happen?

Most neurological disorders are present at birth either due to genetic or environmental factors, e.g. spina bifida or hydrocephalus (fluid in the brain) or Foetal Alcohol Syndrome. Disorders that are acquired after birth are rarer and can be caused by serious infections or traumatic injuries.

What is neurological and neurodevelopmental research?

Basic research

Scientists investigate the biology of the brain and nervous system, how they work together and the pathology (nature and cause) of the disease or disorder

Clinical research

Via lab-based research, scientists and physicians can trial and test new ways of preventing, treating, slowing or curing neurological conditions, e.g. developing new drugs, trying new surgical techniques, gene therapy, immunology or stem cell treatments.

Translational research

Taking the findings from basic science and clinical research in the lab into real-world scenarios and practice.

Did you know?

Approximately children in New Zealand 100 are diagnosed with hydrocephalus each year.


Here are just some of the research projects we are funding to help improve neurological and neurodevelopmental health for New Zealand kids.

Improving the lives of children with hydrocephalus

Hydrocephalus is an abnormal build-up of fluid around the brain. Approximately 100 paediatric patients in New Zealand are diagnosed with hydrocephalus every year making it the most common paediatric neurosurgical condition. Professor Malpas and his team are developing a much-needed ‘pressure sensor device’ to let parents and caregivers monitor their child’s brain pressure remotely. The tool will reduce hospitalisations and radiation exposure from CT scans, and greatly relieve the anxiety of parents around the care of their children.

A quest to find the genes responsible for childhood epilepsies

Epilepsy is the most common serious neurological illness of children and young people. And although kids with epilepsy may live relatively unaffected lives, one third will have seizures with major social, psychological, physical and cognitive consequences. Many of these seizures cannot be controlled by medication and severe epilepsies starting in childhood have a mortality rate of 25% by 20 years of age. 

Professor Lynette Sadleir is a paediatric neurologist specialising in epilepsy. Lynette and her team are studying families where several individuals have epilepsy or where a certain child has an especially severe form. The purpose being to analyse each family’s history and determine the mode of inheritance of the epilepsy

Developing a mindfulness treatment for children with ADHD (attention deficit disorder)

ADHD is a common and debilitating neurodevelopmental disorder that affects 5 to 10% of New Zealand children. It is associated with higher rates of mood disorders, anxiety disorders, defiance disorders, risk-taking behaviour, and criminal offending.

Dr Mairin Taylor and her team will adapt an established mindfulness programme (MyMind) into a proposed ADHD treatment programme called MindKiwi. Their work will adapt a Kaupapa Māori framework – including Te Reo Māori and Tikanga principles – and once successfully adapted, the research team will examine its effectiveness with New Zealand children.


Benjamin was diagnosed with Spina Bifida Myelomeningocele and Hydrocephalus at his Mum Catherine’s 20-week antenatal anatomy scan. The family knew they had a battle on their hands but were determined to do everything they could for their little boy.

Ben and Mum qualified for a ground-breaking fetal surgery in Brisbane, Australia (Mater Mother’s Hospital) to help close the opening in his spine. At 24 weeks gestation, he was the first unborn kiwi and 3rd overall in Australasia to have this surgery.

Due to some complications post-surgery, Benjamin was born at 33 weeks gestation. In the first week of his life, he had an MRI scan and a very large fluid-filled cyst called a syrinx was found in his neural tube in his spine. Untreated this may have caused tetraplegia so a ventriculoperitoneal shunt (VP shunt) was inserted in his brain to relieve the pressure of the syrinx. Since then he has had three shunt revision surgeries, a decompression, and a syringo arachnoid shunt placement.

During the early stages of his diagnosis in pregnancy, Ben’s family were told he would potentially not have any movement of his legs. However, Benjamin can walk with a walker and crutches and is cognitively meeting all his milestones. He is such a happy, bubbly and gentle boy.

“He loves playing with his older brother Jackson. Benjamin is a little miracle and we are so lucky to have him,” Catherine says.

Help fund researchers like Simon.

Every cent helps, no matter how small.